Overcoming cardiac pacemaker "source-sink mismatch"

Instead of complication-prone electronic cardiac pacemakers, biomedical engineers at Georgia Tech and Emory envision the creation of “biological Read more

Hope Clinic part of push to optimize HIV vaccine components

Ten years ago, the results of the RV144 trial– conducted in Thailand with the help of the US Army -- re-energized the HIV vaccine field, which had been down in the Read more

Invasive cancer cells marked by distinctive mutations

What does it take to be a leader – of cancer cells? Adam Marcus and colleagues at Winship Cancer Institute are back, with an analysis of mutations that drive metastatic behavior among groups of lung cancer cells. The findings were published this week on the cover of Journal of Cell Science, and suggest pharmacological strategies to intervene against or prevent metastasis. Marcus and former graduate student Jessica Konen previously developed a technique for selectively labeling “leader” Read more

CTSA

NIH director visits Emory, Atlanta Clinical & Translational Science Institute

David Stephens, MD, Jim Wagner, PhD, Earl Lewis, PhD, Francis Collins, MD, PhD

Dr. Francis Collins, director of the National Institutes of Health, and chief of staff Dr. Kathy Hudson, paid a daylong visit to Emory’s Woodruff Health Sciences Center, including Yerkes National Primate Research Center, and Morehouse School of Medicine on April 14.

The purpose of Collins’ visit was to view the activities of the Atlanta Clinical and Translational Science Institute, one of 46 national CTSAs funded by the NIH through the National Center for Research Resources (NCRR).  Collins also will visit CTSAs at Duke, UNC, and Vanderbilt in the future.

Collins asked that his visit focus on “how CTSAs are enabling science.” It was an opportunity for the ACTSI, a partnership among Emory, Morehouse School of Medicine, Georgia Institute of Technology and others, including Children’s Healthcare of Atlanta, Georgia Research Alliance, Georgia BIO, Kaiser Permanente, CDC, the Atlanta VA Medical Center and the Grady Health System, to showcase the unique contributions the ACTSI makes to enabling clinical and translational research.

Read more

Posted on by Holly Korschun in Uncategorized Leave a comment

Gaining better medicine in translation

 

David Stephens, MD

David Stephens, MD

Translational research has traditionally been thought of as the process of moving a discovery in one direction – from the laboratory to the patient. More recently, though, researchers have recognized the importance of community engagement in the biomedical discovery process. That’s because involving the community makes for better medical care for patients.

The Atlanta Clinical and Translational Science Institute (ACTSI) is a partnership of educational, research, and health care institutions that involves the community in clinical research that translates laboratory discoveries into advanced treatments for patients. The ACTSI is part of the Clinical and Translational Science Awards (CTSA) of the National Center for Research Resources (NCRR) of the National Institutes of Health.

The ACTSI’s goal of supporting more effective clinical and translational research has led to a broader definition of translation: discovering what new healthcare tools, diagnostic tests and therapies a community needs and then taking that information back to the laboratory or conducting clinical research to find ways to meet those needs.

David Stephens, MD, is principal investigator of the ACTSI. Stephens says community engagement brings together leaders who discuss the health care needs of their respective communities. Researchers can then periodically meet with leaders, and let them know what progress is being made in the laboratory.

The ACTSI also brings together laboratory scientists with clinical investigators, community clinicians, professional societies and industry collaborators in a wide variety of research projects.

The ACTSI is led by Emory University, along with Morehouse School of Medicine, the Georgia Institute of Technology, Children’s Healthcare of Atlanta, and Kaiser Permanente Georgia. Other partners include the Centers for Disease Control and Prevention, Grady Health System, the Georgia Research Alliance, Georgia Bio, the Atlanta Veterans Affairs Medical Center, and the American Cancer Society.

To hear Stephens’ own words about translational research and the ACTSI, listen to Emory University’s Sound Science podcast.

Posted on by Robin Tricoles in Uncategorized Leave a comment