Genomics plus human intelligence

The power of gene sequencing to solve puzzles when combined with human Read more

'Master key' microRNA has links to both ASD and schizophrenia

Recent studies of complex brain disorders such as schizophrenia and autism spectrum disorder (ASD) have identified a few "master keys," risk genes that sit at the center of a network of genes important for brain function. Researchers at Emory and the Chinese Academy of Sciences have created mice partially lacking one of those master keys, called MIR-137, and have used them to identify an angle on potential treatments for ASD. The results were published this Read more

Shape-shifting RNA regulates viral sensor

OAS senses double-stranded RNA: the form that viral genetic material often takes. Its regulator is also Read more

technology transfer

The next generation of biomedical engineering innovators

Congratulations to the winners of the InVenture innovation competition at Georgia Tech. The competition aired Wednesday night on Georgia Public Broadcasting. The winners get cash prizes, a free patent filing and commercialization service through Georgia Tech’s Office of Technology Transfer.

Several of the teams have Emory connections, through the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory, and the Atlanta Clinical & Translational Science Institute.

Emergency medical professionals know that intubation can be rough. The second place ($10,000) MAID team created a “magnetic assisted intubation device” that helps them place a breathing tube into the trachea in a smoother way. The MAID was designed by Alex Cooper, Shawna Hagen, William Thompson and Elizabeth Flanagan, all biomedical engineering majors. Their clinical advisor was Brian Morse, MD, previously a trauma fellow and now an Emory School of Medicine surgical critical care resident at Grady Memorial Hospital.

“When I first saw the device that the students had developed, I was blown away,” Morse told the Technique newspaper. “It’s probably going to change the way we look at intubation in the next five to 10 years.”

The AutoRhexis team, which won the People’s Choice award ($5,000), invented a device to perform the most difficult step during cataract removal surgery. It was designed by a team of biomedical and mechanical engineering majors: Chris Giardina, Rebeca Bowden, Jorge Baro, Kanitha Kim, Khaled Kashlan and Shane Saunders. They were advised by Tim Johnson, MD, who was an Emory medical student and is now a resident at Columbus Regional Medical Center.

The finalist Proximer team, advised by Emory surgeon Albert Losken, MD, developed a way to detect plastics in the body, which can help breast cancer survivors undergoing reconstruction.

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Federal research funding sparks economic growth

A recent report from The Science Coalition gives numerous examples of how federally funded research at universities has led to innovation, new companies, and the creation of jobs. The Sparking Economic Growth report lists the university research origins of 100 companies, including Google, Genentech, Cisco Systems and iRobot. Four Emory startup companies were highlighted among the success stories: GeoVax, Inc., Pharmasset, Inc., Syntermed, Inc., and Triangle Pharmaceuticals, which was later acquired by Gilead Sciences in California.

Emory President James Wagner wrote a followup editorial in the Atlanta Business Chronicle about the importance of scientific research in Georgia’s universities to the health of our economy.

“Atlanta can be proud that Emory University is a shining example in this report, with four highlighted successful companies that were launched because federally funded research resulted in innovative and life-saving discoveries. These four success stories only scratch the surface as examples of the more than 150 companies and the resulting 5,500 jobs created in Georgia from discoveries at its research universities.

“Since the 1990s, Emory has turned external research funding, the majority from the federal government, into more than $775 million in licensing revenues from drugs, diagnostics, devices and consumer products. This is money infused into the state’s economy that helps create jobs and educational opportunities, saves lives, and leads to more research discoveries for the benefit of all. Emory has launched 47 start-up companies and licensed 27 drugs, medical devices and diagnostics already in the marketplace and 12 more currently in human trials.”

GeoVax, Inc., is developing and testing a promising AIDS vaccine based on research at the Emory Vaccine Center and Yerkes National Primate Research Center. Gilead Sciences (from Triangle Pharmaceuticals) and Pharmasset, Inc. are creating AIDS drugs that are taken by over 90 percent of HIV-infected patients in the United States and many more around the world. Syntermed, Inc. distributes imaging software developed at Emory that helps in the diagnosis of more than four million heart disease patients every year.

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CPR Manikins Make Training Easier

Studies have consistently found that cardiopulmonary resuscitation (CPR) performed immediately by a bystander doubles or even triples a cardiac arrest victim’s chance of survival.

To increase the rate of bystander CPR, the American Heart Association recently modified its CPR guidelines so that it is now permissible to provide continual chest compressions without mouth-to-mouth rescue breathing. This makes CPR easier and may even produce better results.

Arthur Kellermann, MD, MPH

Arthur Kellermann, MD, MPH, formerly an emergency medicine physician and associate dean for public policy at Emory, and David Sanborn, a mechanical engineer at Georgia Tech, have invented a low-cost CPR manikin to help anyone learn and practice compression-only CPR. Kellermann currently is director of the Program in Public Health Systems and Preparedness and Paul O’Neill-Alcoa Chair in Policy Analysis at the RAND Corporation in Virginia.

Their work builds on Emory research that showed laypeople could teach themselves CPR at home using a 25-minute video with results that are comparable to taking a four-hour course taught by a professional instructor.

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The Bayh-Dole Act: 30 Years of Innovation

At Emory’s recent Fourth Celebration of Technology and Innovation, faculty researchers and entrepreneurs were recognized for outstanding accomplishments in developing promising technologies that are moving from the laboratory to the marketplace.

Keynote speaker for the annual event was Joseph Allen, a key staff member in helping Senator Birch Bayh (D-IN) secure passage of the Bayh-Dole Act 30 years ago, opening up collaborations between research universities and U.S. industry.

Todd Sherer, executive director of Emory’s Technology Transfer Office, described Emory’s robust product pipeline, which includes products at all stages of development and regulatory approval. The pipeline helps ensure multiple missions of driving academic discoveries, advancing commercially protected technologies, and providing substantial public benefit.

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