Multiple myeloma patients display weakened antibody responses to mRNA COVID vaccines

Weakened antibody responses to COVID-19 mRNA vaccines among most patients with multiple Read more

Precision medicine with multiple myeloma

“Precision medicine” is an anti-cancer treatment strategy in which doctors use genetic or other tests to identify vulnerabilities in an individual’s cancer subtype. Winship Cancer Institute researchers have been figuring out how to apply this strategy to multiple myeloma, with respect to one promising drug called venetoclax, in a way that can benefit the most patients. Known commercially as Venclexta, venetoclax is already FDA-approved for some forms of leukemia and lymphoma. Researchers had observed that multiple Read more

Promiscuous protein droplets regulate immune gene activity

Biochemists at Emory are achieving insights into how an important regulator of the immune system switches its function, based on its orientation and local environment. New research demonstrates that the glucocorticoid receptor (or GR) forms droplets or “condensates” that change form, depending on its available partners. The inside of a cell is like a crowded nightclub or party, with enzymes and other proteins searching out prospective partners. The GR is particularly well-connected and promiscuous, and Read more

Jean-Michel Vigreux

Global climate change and health risks

Public health experts, including researchers, practitioners and policy makers from Emory, CARE, the Centers for Disease Control and Prevention (CDC), and other public and private organizations met at Emory recently for a symposium focusing on the health risks associated with global climate change.

Climate change is affecting the growth of crops, access to water, floods, malnutrition, and the prevalence of disease.

The goal was to form an agenda to develop the tools, policies, and approaches needed to address climate health risks and incorporate climate change adaptation into global health and development work.

And for good reason: right now climate change is contributing to the destruction of livelihoods and the aggravation of social inequalities, said speaker Jean-Michel Vigreux. Vigreux, CARE’s senior vice president of program quality and impact, said climate change is affecting the growth of crops, access to water, floods, malnutrition, and the prevalence of disease–especially climate sensitive disease. All this, he says, disproportionately affects the poor and other vulnerable populations.

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