Revealing brain temperature via MR imaging and biophysical modeling

A combination of MRI and biophysical modeling could provide more accurate predictions of brain Read more

Trailblazer award for MR monitoring brain temperature

NIBIB R21 "Trailblazer" award to monitor brain temperature while patients undergo therapeutic hypothermia after cardiac Read more

COVID-19 vaccine-generated antibodies last at least 6 months

How long does COVID-19 vaccine-generated immunity last? New laboratory results provide a partial answer to that Read more

longevity

Unexpected mechanism for a longevity lipid

The idea that particular lipid components, such as omega-3 fatty acids, promote health is quite familiar, so the finding that the lipid oleoylethanolamide or OEA extends longevity in the worm C. elegans is perhaps not so surprising. However, a recent paper in Science is remarkable for what it reveals about how OEA exerts its effects.

Scientists at Baylor College of Medicine led by Meng Wang, with some help from biochemists Eric Ortlund and Eric Armstrong at Emory, discovered that OEA is a way one part of the cell, the lysosome, talks to another part, the nucleus. Lysosomes are sort of recycling centers/trash digesters (important for autophagy) and the nucleus is the control tower for the cell. The authors show that starting in lysosomes, OEA travels to the nucleus and activates nuclear hormone receptors (the Ortlund lab’s specialty). Read more

Posted on by Quinn Eastman in Uncategorized Leave a comment