Mapping the cancer genome wilderness

A huge cancer genome project has highlighted how DNA that doesn’t code for proteins is still important for keeping our cells on Read more

Stem-like CD8 T cells stay in lymph nodes/spleen

Virus-specific CD8 T cells accumulate in lymph nodes and in other organs, without circulating in abundance in the Read more

To fight cancer, mix harmless reovirus with 'red devil'

The GDBBS symposium included a talk about the next step: attaching the souped-up reovirus to Read more

Karl Deisseroth

Manipulating neurons with light

Welcome to a feature of Lab Land we hope to have on a regular basis! It’s where we explain a word or phrase that is a hot topic of discussion in the science online world and particularly relevant to research going on at Emory.

Optogenetics allows researchers to stimulate specific brain cells with light. It involves introducing light-sensitive proteins from algae into the brain cells of mice, and then using a fiber optic cable to apply a laser signal to the relevant region of the brain.

Optogenetics is a leap beyond previous genetic engineering techniques that made it possible to turn on (or delete) a gene by feeding a mouse some extraneous chemical, such as the antibiotic tetracycline or the anti-hormone tamoxifen. Instead of wondering how long it takes that chemical to make its way into the brain, scientists can literally flick a switch and see near-instantaneous and localized effects. Read more

Posted on by Quinn Eastman in Neuro Leave a comment