NINDS supporting Emory/UF work on myotonic dystrophy

NINDS grant will support collaboration between Gary Bassell and Eric Wang on myotonic Read more

Antios moving ahead with potential drug vs hepatitis B

Antios Therapeutics is moving ahead clinical studies of an antiviral drug aimed at hepatitis Read more

Traynelis lead researcher on CureGRIN/Chan Zuckerberg award

The CureGRIN Foundation works closely with Emory pharmacologist Stephen Traynelis, who has been investigating rare genetic disorders affecting NMDA Read more

Emory+Childrens Pediatric Research Center

Autoimmune gene link for subtype of juvenile arthritis

Geneticist Sampath Prahalad and the families he works with were part of this recent PNAS paper, which probes genetic risk factors for systemic juvenile idiopathic arthritis.

There are several subtypes of juvenile arthritis, and sJIA (systemic juvenile idiopathic arthritis) sounds especially painful because of its inflammatory symptoms: daily spiking fever and skin rashes in addition to joint pain.

The international team of investigators assembled what they report as the largest collection of sJIA patients (close to 1000) and identified HLA-DRB1*11 as a genetic risk factor for sJIA.

HLA-DRB1 alleles have also been linked to autoimmune diseases such as multiple sclerosis, type I diabetes and (adult) rheumatoid arthritis. The finding strengthens the case for trying existing medications that target T cell activation in sJIA. Read more

Posted on by Quinn Eastman in Immunology Leave a comment