If we want to understand how the brain creates memories, and how genetic disorders distort the brain’s machinery, then the fragile X gene is an ideal place to start. That’s why the Stephen T. Warren Memorial Symposium, taking place November 28-29 at Emory, will be a significant event for those interested in neuroscience and genetics.
Stephen T. Warren, 1953-2021
Warren, the founding chair of Emory’s Department of Human Genetics, led an international team that discovered Read more
At a time when COVID-19 appears to be receding in much of Georgia, it’s worth revisiting the start of the pandemic in early 2020. Emory virologist Anne Piantadosi and colleagues have a paper in Viral Evolution on the earliest SARS-CoV-2 genetic sequences detected in Georgia.
Analyzing relationships between those virus sequences and samples from other states and countries can give us an idea about where the first COVID-19 infections in Georgia came from. We can draw Read more
For adult organ transplant recipients, juggling a lifetime regimen of immunosuppressant drugs is difficult enough, but for children it presents an even greater challenge.Â These drugs, which also can have toxic side effects, must strike a delicate balance between preventing organ rejection and protecting from infections.
But childrenâ€™s immune systems are still â€œlearningâ€ what distinguishes them from the world around them, and children are constantly developing and changing, both physically and emotionally. This puts them at greater risk for complications either through inappropriate medication or failure to take these drugs properly.
The ARRA-funded project will not only help determine which medications children should take, but also will give them the support to care for their transplanted organs.Â The Emory scientists are studying new biological monitoring technologies that can identify unique ways to determine exactly how much medication a child really needs. These studies are being combined with a novel transition care clinic specializing in helping children cope with their illness and assuming responsibility for their care.
â€œThis award indicates exceptional insight by the NIAID into the critical link between a childâ€™s physical well-being and their emotional maturity,â€ says Kirk. â€œIt will accelerate progress in this vital area of research for a very deserving subset of chronically ill children.â€
The grant will allow Childrenâ€™s and Emory to expand their research partnership, attract top scientists, and advance research discoveries that will improve the health of children.
Some of the pediatric research conducted in a new building to be built on the Emory campus will focus on cardiology, cancer, vaccines, and new drug discovery. The grant has implications for the city of Atlanta as a growing research community, building on collaborations among Childrenâ€™s Healthcare, Emory, Georgia Institute of Technology, Morehouse School of Medicine, and others.
Fred Sanfilippo, MD, PhD, executive vice president for health affairs at Emory, and Donna W. Hyland, president and CEO of Children’s Healthcare of Atlanta, explained that the new grant, which is the largest single gift ever to Children’s, will have an enormous impact on the two institutions, building on the strong partnership between Emory and Children’s and leading them to become a major pediatric research hub in the Southeast and the nation. Most importantly, it will help in finding cures for some of the most common and devastating childhood diseases.
Knechtle is chief of the Emory School of Medicine transplant division and professor of surgery, and surgical director of Childrenâ€™s Liver Transplant Program. Childrenâ€™s Liver Transplant program was founded in 1990 and has completed more than 300 liver transplants.
The liver transplant team is made up of many individuals who contribute to its success – liver transplant surgeons, transplant hepatologists (doctors with expertise in the treatment of the liver), and a team of gastroenterologists, anesthesiologists, pathologists, radiologists, mental health specialists, chaplains, nurses, social workers and pharmacists.
For more than 20 years, Emory and Childrenâ€™s physicians have been at the forefront of pediatric transplant care, achieving several groundbreaking accomplishments, including:
Transplanted the worldâ€™s youngest (10 days old) and three smallest (2 to 4 pounds) liver transplant recipients
One of the first pediatric hospitals in the United States to perform three heart transplants in 24 hours
At the forefront of its field with ABO-incompatible liver and heart transplants
Performed more than 450 pediatric kidney transplants.
Children’s kidney transplant recipient Quinn Roberts, age 8, with her donor Cheryl Thomas