Tracing the start of COVID-19 in GA

At a time when COVID-19 appears to be receding in much of Georgia, it’s worth revisiting the start of the pandemic in early 2020. Emory virologist Anne Piantadosi and colleagues have a paper in Viral Evolution on the earliest SARS-CoV-2 genetic sequences detected in Georgia. Analyzing relationships between those virus sequences and samples from other states and countries can give us an idea about where the first COVID-19 infections in Georgia came from. We can draw Read more

Reddit as window into opioid withdrawal strategies

Drug abuse researchers are using the social media site Reddit as a window into the experiences of people living with opioid addiction. Abeed Sarker in Emory's Department of Biomedical Informatics has a paper in Clinical Toxicology focusing on the phenomenon of “precipitated withdrawal,” in collaboration with emergency medicine specialists from Penn, Rutgers and Mt Sinai. Precipitated withdrawal is a more intense form of withdrawal that can occur when someone who was using opioids starts medication-assisted treatment Read more

CROI: HIV cure report and ongoing research

The big news out of CROI (Conference on Retroviruses and Opportunistic Infections) was a report of a third person being cured of HIV infection, this time using umbilical cord blood for a hematopoetic stem cell transplant. Emory’s Carlos del Rio gave a nice overview of the achievement for NPR this morning. As del Rio explains, the field of HIV cure research took off over the last decade after Timothy Brown, known as “the Berlin patient,” Read more

bacteria. fluorescence

A spoonful of sugar helps infection detection

Congratulations to Kiyoko Takemiya, a postdoctoral fellow in Emory’s Division of Cardiology, working with W. Robert Taylor. At the recent American College of Cardiology meeting in Washington DC, she won first place in the competition for an ACC Foundation/ Herman K. Gold Young Investigators Award in Molecular and Cellular Cardiology.

The title of her research presentation was: A Novel Imaging Probe for the Detection of Subclinical Bacterial Infections Involving Cardiac Devices.

Takemiya, Taylor, and their colleagues (including Mark Goodman and Niren Murthy, formerly at Georgia Tech and now at UC Berkeley) developed a fluorescent probe that allows the detection of small levels of bacteria on cardiac devices. The probe was tested in rats, some of which had relatively mild local S. aureus infections. The fluorescent probe (PET is also under investigation) makes use of the properties of maltohexaose, a sugar that is taken up by bacteria but not mammalian cells.

Infection rates for implantable cardiac devices such as pacemakers have been rising, according to a 2012 paper in NEJM.

Posted on by Quinn Eastman in Heart Leave a comment