At the sleep research meeting in San Antonio this year, there were signs of an impending pharmaceutical arms race in the realm of narcolepsy.
The big fish in a small pond, Jazz Pharmaceuticals, was preparing to market its recently FDA-approved medication: Sunosi/solriamfetol. Startup Harmony Biosciences was close behind with pitolisant, already approved in Europe. On the horizon are experimental drugs designed to more precisely target the neuropeptide deficiency in people with classic narcolepsy type 1 Read more
An anti-inflammatory drug called ketorolac, given before surgery, can promote long-term survival in animal models of cancer metastasis, a team of scientists has found. The research suggests that flanking chemotherapy with ketorolac or similar drugs -- an approach that is distinct from previous anti-inflammatory cancer prevention efforts -- can unleash anti-tumor immunity.
The findings, published in Journal of Clinical Investigation, also provide a mechanistic explanation for the anti-metastatic effects of ketorolac, previously observed in human Read more
Emory is full of fledgling biomedical proto-companies. Some of them are actual corporations with employees, while others are ideas that need a push to get them to that point. Along with the companies highlighted by the Emory Biotech Consulting Club, Dean Sukhatme’s recent announcement of five I3 Venture research awards gives more examples of early stage research projects with commercial potential.
This is the third round of the I3 awards; the first two were Wow! Read more
Emory University and Children’s Healthcare of Atlanta pediatric physician Dr. Mark Wulkan is among the first surgeons in Georgia to perform single-site incision surgery on pediatric patients for routine surgeries.
Dr. Mark Wulkan
Dr. Wulkan is using this method for multiple procedures, including appendectomy, removal of the spleen, and stomach surgery.
Traditional laparoscopic surgical incisions are made in different locations on the abdominal wall, resulting in several small scars. The single-site method, however, is considered scarless because only one incision is made in the belly button and is typically difficult to see. Pediatric patients who undergo single-site procedures enjoy all the benefits of laparoscopic surgery, such as rapid recovery and less pain than that associated with traditional open surgery.
Berns says, “We all live in groups. Sometimes groups make good decisions, but groups often behave worse than any of its members would. Weâ€™re approaching the problem of collective decision-making from a new perspective by studying how the human brain functions in groups.â€
Center members advise decision-makers of all kinds by conducting experiments focused on biologically based pressures that influence collective decision-making. Through their discoveries, researchers will better understand how culture, intelligence and environment influence the way decisions are made and how basic human tendencies drive judgment in certain situations.
As Berns points out, people also need to understand how religious and political ideologies become transformed in the brain and can subvert basic self-survival value judgments, a phenomenon that occurs in war and terrorism.
â€œCollective decision-making is political, but politics are biological,â€ says Berns. â€œThe human brain evolved to function in social groups. By discovering how our brains are wired to behave in groups, we can find solutions to problems of global impact.â€Berns is the author of Satisfaction: The Science of Finding True Fulfillment and Iconoclast: A Neuroscientist Reveals How to Think Differently.
Over the past twenty years, the research partnership between Emory University and the Georgia Institute of Technology has developed into one of the leading bioengineering and biomedical research and educational programs in the nation. In recent years this partnership has resulted in the development of several pieces of diagnostic and medical-assistant technology, with medical experts on the Emory side working with engineers on the Georgia Tech side.
An example of this collaboration is the El-E robot, designed to perform simple tasks such as opening drawers and retrieving objects. Clinicians at Emoryâ€™s School of Medicine and engineers at Georgia Tech created the 5Â½-foot-tall machine, which glides across the floor on wheels and takes direction from a laser pointer that users can control in a variety of ways, depending on their preferences and capabilities. El-E is no mere toy, however: The machine could help patients with significant motor impairments, such as sufferers of ALS, maintain their independence and help relieve physical and financial burdens faced by caregivers.
Another result of the Emory-Georgia Tech collaboration is DETECT, a portable device capable of detecting the earliest stage of Alzheimer’s disease, mild cognitive impairment, in any environment. DETECT has a helmet device that includes an LCD display in a visor, along with a computer and noise-reduction headphones. DETECT gives the patient a battery of words and pictures to assess cognitive abilitiesâ€”reaction time and memory capabilities. The low-cost test takes approximately 10 minutes. The device was co-developed by emergency medicine physician David Wright, and Michelle LaPlaca, a scientist in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory.
Millions of TV viewers know Dr. Sanjay Gupta as CNN’s chief medical correspondent. But did you know that off the air, Dr. Gupta is a practicing trauma neurosurgeon at nearby Grady Memorial Hospital? Gupta, like most of the doctors at the hospital, is an Emory physician. CNN medical producer Danielle Dellorto put together this video showing what his life as a surgeon is like.
China is likewise reaching out to Emory. According to the international business news site Global Atlanta, delegates from Chinaâ€™s Shandong province recently came to Atlanta to meet with health care professionals, public health officials, educational institutions and legislators.The group visited the the Emory Spine Center, where they met with acupuncturists using traditional Chinese techniques alongside new therapies.
You or a loved one is suffering severe brain trauma in the wake of an accident. Imagine if doctors told you there was a treatment available that could up your chances of survival and even your chances at recovery. This isn’t just theoretical, because that’s an option some Emory patients have had, thanks to the availability of PROTECT, a progesterone-based treatment developed at Emory University and being administered by Emory trauma doctors.
If you watch the 8 a.m. hour of Fox 5 Atlanta’s “Good Day Atlanta,” you can see Grady Hospital-based internal medicine physicians Neil Winawer and Kimberly Manning. The doctors dispense medical information on Mondays and Wednesdays each week from the set of Fox 5’s “Good Day Housecall.” Following a crash course in broadcast journalism, the doctors research and write their own segments. Recent topics include swine flu,emergency contraception,brain trauma, and fitness in your 40s.
Manning joined the Emory faculty in 2001 and is program director for maglie calcio poco prezzo Transitional Year Residency Program. Winawer, who is Manning’s faculty mentor, has been at Emory for 13 years Both doctors work at Grady Memorial Hospital in Downtown Atlanta. Read more about “Housecalls” on the Emory-Grady web site.