H1N1 2009 virus may point way to universal flu vaccine

Emory MedicalHorizon

Scientists at Emory and the University of Chicago have discovered that the 2009 H1N1 flu virus provides excellent antibody protection. This may be a milestone discovery in the search for a universal flu vaccine.

Researchers took blood samples from patients infected with the 2009 H1N1 strain and developed antibodies in cell culture. Some of the antibodies were broadly protective and could provide protection from the H1N1 viruses that circulated over the past 10 years in addition to the 1918 pandemic flu virus and even avian influenza or bird flu (H5N1).

The antibodies protected mice from a lethal viral dose, even 60 hours post-infection.

The research is published online in the Journal of Experimental Medicine.

Some of the antibodies stuck to the “stalk” region, or hemagglutinin (H in H1N1) protein part of the virus. Because this part of the virus doesn’t change as much as other regions, scientists have proposed to make it the basis for a vaccine that could provide broader protection. The antibodies could guide researchers in designing a vaccine that gives people long-lasting protection against a wide spectrum of flu viruses.

The paper’s first author, Emory School of Medicine’s Jens Wrammert, PhD, says “Our data shows that infection with the 2009 pandemic influenza strain could induce broadly protective antibodies that are very rarely seen after seasonal flu infections or flu shots. These findings show that these types of antibodies can be induced in humans, if the immune system has the right stimulation, and suggest that a pan-influenza vaccine might be feasible.”

Rafi Ahmed, PhD, director of the Emory Vaccine Center, and a Georgia Research Alliance Eminent Scholar, is co-senior author of the publication, along with Patrick Wilson at University of Chicago.



  • See YouTube for video commentary by Dr. Ahmed
  • For access to raw video for media purposes, contact Kathi Baker, kobaker@emory.edu, 404-727-9371 Office, 404-686-5500 Pager (ID 14455), 404-227-1871 Mobile.


Be Sociable, Share!

Posted on by Jennifer Johnson in Immunology 2 Comments

About the author

Jennifer Johnson

Associate Director, Media Relations jennifer.johnson@emory.edu 404-727-5696 Office 404-686-5500 Pager (ID 13828) 404-227-3683 Mobile

Add a Comment

  • Feedback

    Let us know what you think.

    You can contact us via the email button below or you can use our online feedback form You can also leave comments directly on individual posts.

buy windows 8 personalization enabler key cheap,buy windows 8 crack key key online,Windows 8 Activator,cheap Windows 7 Ultimate Activation Key buy Windows 8.1 Product Key Finder 2014 key online,buy windows 8 build 9200 activator free download key online,buy Windows 8 Activator key cheap,buy How to Activate Windows 8 For Free key cheap,cheap Windows 8 Professional Activation Key download buy Keyword key online,buy linux server software key cheap,buy windows crack key online,Windows Server 2012 Standard Activation Key buy windows office 2013 professional cheap,cheap ms office 365,ms office 2010 cheap download,download visio,buy office 2013 package cheap,buy office 2013 package cheap buy download office 2013 with product key cheap,2013 office product key,office 2013 for free download cheap download,ms office pro cheap download,microsoftproject free office trial,buy office 2010 access cheap,office 2013 online download cheap download,ms office professional Windows 8 Professional,buy Windows 7 key cheap,Windows 8 Enterprise Activation Key,buy small business server key cheap,cheap windows 8.1 buy Windows 8.1 loader 2013 key cheap,buy Windows 8.1 Permanent Activator free 2013 key cheap,buy Activate Windows 8 PRO and Enterprise Build 9200 key online,cheap Windows 7 Home Basic Activation Key download,cheap Windows 7 Professional SP1 Activation Key download buy windows server upgrade key cheap,buy windows 8 pro build 9200 product key key cheap,buy Download Kms Activator Windows 8 Build 8400 key online,buy windows 8 personalization working key cheap buy office 2010 home & business cheap,office software free cheap download,download of office 2013,is visio part of office 2013,buy windows office 2007 cheap buy office 365 office 2013 cheap,office download 2010,buy windows office professional cheap,office standard 2010,buy office professional plus 2013 cheap office pro 2013 plus cheap download,buy free download office word cheap,buy office home 2013 cheap,cheap latest ms office 2013 free download cheap free download office word 2013,where can i download office 2013,buy office 2013 trial version free download cheap,cheap outlook 2007 office pro 2013 plus cheap download,buy free download office word cheap,buy office home 2013 cheap,cheap latest ms office 2013 free download buy windows server learning key online,upgrade windows server,buy windows server 2008 requirements key online,data center windows 8 pro crack,cheap windows 8 pro download,Windows 7 activator free Download,buy windows 7 activation crack key cheap,buy windows 2003 servers key online,buy windows 2003 servers key online buy windows server 2008 enterprise key online,cheap Windows 7 Ultimate Activation Key download,windows business server,buy Windows 7 Pro & Enterprise 32 bit and 64 bit activator key cheap,buy windows 10 free activator key cheap skype software free download for windows 7 full version,cheap windows 8.1 pro download,windows 2008 r2,Windows 8 Pro & Enterprise 32 bit and 64 bit Activator,windows 7 home buy windows 8 crack key online,cheap Windows Server 2012 Datacenter Activation Keywindows 7,Windows 8.1 Permanent Activator free 2013 buy windows 8 crack key online,cheap Windows Server 2012 Datacenter Activation Keywindows 7,Windows 8.1 Permanent Activator free 2013 buy new windows version key online,buy windows 7 loader free download key online,windows home server 2011 Windows 7 Enterprise SP1 Activation Key,buy windows 7 certification key cheap,buy windows 8 crack download free key online,buy windows 7 activation key free download key cheap,buy server operating systems key online Windows 8.1 Activator Loader,buy windows server services key online,buy windows 8 activator 2014 key cheap,buy win 7 activator 2014 key online