Mysterious DNA modification important in fly brain

Drosophila, despite being a useful genetic model of development, have very little DNA methylation on C. What they do have is methylation on A (technically, N6-methyladenine), although little was known about what this modification did for Read more

Where it hurts matters in the gut

What part of the intestine is problematic matters more than inflammatory bowel disease subtype (Crohn’s vs ulcerative colitis), when it comes to genetic activity signatures in pediatric Read more

Overcoming cisplatin resistance

Cisplatin was known to damage DNA and to unleash reactive oxygen species, but the interaction between cisplatin and Mek1/cRaf had not been observed Read more

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Healthy lifestyle can lower blood pressure

A new study says that maintaining normal weight, daily vigorous exercise, eating a diet high in fruits, vegetables, low-fat dairy products and low in sodium, and taking a folic acid supplement is linked with lowering hypertension in women.

A healthy lifestyle helps your heart

A healthy lifestyle helps your heart

Reporting in the July 22/29 issue of the Journal of the American Medical Association, scientists say that hypertension, or high blood pressure, contributes to more excess deaths in women than any other preventable factor. The researchers looked at the link between combinations of low-risk lifestyle factors and the risk of developing hypertension.

Allen Dollar, MD, preventive cardiologist with Emory Heart & Vascular Center, says the study by Harvard Medical School researchers points to the real benefit to women of deploying a healthy lifestyle to prevent hypertension or to control hypertension.

Essentially, this new report helps to confirm what preventive cardiologists share with women everyday, says Dollar, that they can help prevent or manage hypertension through a healthy approach to diet and exercise.

Generally, blood pressure above 140/90 is considered to be high for adults. Although hypertension can produce symptoms including fatigue, confusion, nausea, vision http://www.agfluide.com problems and excessive sweating, Dollar points out that the majority of women with mild to moderate hypertension have no symptoms that indicate their blood pressure is too high.

A blood pressure reading can reveal hypertension in the early stages when a strategy of diet changes, exercise and weight control and medication, if needed, can help prevent a host of high blood pressure related ills including heart attacks, heart failure, kidney disease and stroke, says Dollar. If a woman does not know her blood pressure, she needs to find out. If a woman learns she has high blood pressure, she can use this news as an opportunity to take control of her health.

Learn more medical advances at Emory.

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Health care reform: Wise allocation of resources key

Emory’s Chief Quality Officer William Bornstein, MD, PhD, says there are many issues that need to be tackled in order to achieve meaningful health care reform. He points out that one of the most fundamental questions that must be addressed is who decides about a treatment or diagnostic test that may be a little bit better than an alternative option but is much more expensive? If the patient has no “skin in the game,” he will almost certainly want the better/more expensive option.

William Bornstein, MD, PhD

William Bornstein, MD, PhD

The doctor has taken an oath to act in the best interests of the patient and this obligation takes precedence over any charge that society would like to impose to cast the Ray Ban Baratas physician in a fiduciary role for the national healthcare budget, says Bornstein, who also serves as chief medical officer for Emory Hospitals. And, the payer’s role is obviously conflicted, he says. If the patient does have skin in the that decision, Bornstein asks, are we prepared as a society to explicitly endorse the notion that “better” care that exceeds a certain cost threshold will only be available to those who can afford the additional cost?

There has been much talk about better care and preventative care being less expensive, but there are little data that support this as being a universal truth. Health care information ray ban outlet technology will also not solve this problem, he says. At some point in the near future, we need to have a national conversation about this challenge. In the past attempts to have such conversations have raised the specter of “rationing,” However, the time has come to confront the truth that our resources are finite and we need to allocate them wisely.

Bornstein is a recognized leader in quality, safety and the use of information technology in improving healthcare delivery. He has serves on national committees and advisory bodies in these areas including the University HealthSystem Consortium Clinical Evaluative Sciences Council Steering Committee, which he now chairs. He serves on the Professional and Technical Advisory Committee for the hospital accreditation process of The Joint Commission as vice-chair, and on the Information Architecture Steering Committee of the University HealthSystem Consortium staff leadership group of the Institute of Medicine Roundtable on Evidence Based Medicine.

Listen to podcasts with Bornstein on quality.

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Michael J. Fox Foundation supports Emory research

The Michael J. Fox Foundation for Parkinson’s Research just announced plans to fund Emory pharmacology researcher Zixu Mao in his work to validate therapeutic targets for Parkinson’s disease (PD).

Zixu Mao, PhD

Zixu Mao, PhD

The two-year, $250,000 grant will fund research in Mao’s lab in the departments of neurology and pharmacology. He and his team hope to verify whether a particular protein – MEF2D – may be a good drug target in models of PD. If it is, his efforts will provide the basis for further research to identify ways to manipulate the activity of this protein as a way to treat PD.

Mao says this type of study is very important Maglie Calcio to allow the transition from findings made by basic research to more clinically relevant discoveries and is generally difficult to get funded by other major funding sources.

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson’s disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson’s today. Learn more about Mao’s research.

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U.S. News ranks Emory University Hospital

America's Best HospitalsToday, U.S. News and World Report issued the 2009-10 America’s Best Hospitals.

Emory University Hospital ranked among the nation’s best hospitals in 11 specialties. Overall, Emory is one of only 170 hospitals, out of more than 5,400 medical centers in the country to be named in even one of the magazine’s top 50 specialty rankings.

Emory is recognized in this year’s comprehensive report for excellence in:

Specialty and Rank
Ophthalmology – 9
Psychiatry – 10
Geriatrics – 13
Heart and Heart Surgery – 13
Neurology and Neurosurgery – 14
Ear, Nose and Throat – 22
Kidney Disease – 25
Diabetes/Endocrinology – 31
Gynecology – 44
Urology – 44
Cancer – 46

U.S. News says it looks at, “how well these institutions do in complex and demanding situations—replacing an 85-year-old’s heart valve, diagnosing and treating a spinal tumor, and dealing with inflammatory bowel disease, to name three examples. High-stakes medicine calls for more than the usual brand of doctoring.”

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Small, single incision for surgery helps young patients

Emory University and Children’s Healthcare of Atlanta pediatric physician Dr. Mark Wulkan is among the first surgeons in Georgia to perform single-site incision surgery on pediatric patients for routine surgeries.

Dr. Mark Wulkan

Dr. Mark Wulkan

Dr. Wulkan is using this method for multiple procedures, including appendectomy, removal of the spleen, and stomach surgery.

“Single-site surgery takes minimally invasive surgery (laparoscopic surgery) to the next level,” said Dr. Wulkan, is an associate professor of surgery and pediatrics in the Emory University School of Medicine and who performs surgery at Children’s Healthcare of Atlanta at Egleston. “Children leave the operating room with virtually no scars.”

Traditional laparoscopic surgical incisions are made in different locations on the abdominal wall, resulting in several small scars. The single-site method, however, is considered scarless because only one incision is made in the belly button and is typically difficult to see. Pediatric patients who undergo single-site procedures enjoy all the benefits of laparoscopic surgery, such as rapid recovery and less pain than that associated with traditional open surgery.

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Dr. Sanjay Gupta: CNN correspondent & Emory doctor

Millions of TV viewers know Dr. Sanjay Gupta as CNN’s chief medical correspondent. But did you know that off the air, Dr. Gupta is a practicing trauma neurosurgeon at nearby Grady Memorial Hospital? Gupta, like most of the doctors at the hospital, is an Emory physician. CNN medical producer Danielle Dellorto put together this video showing what his life as a surgeon is like.


 

 

Gupta works with Emory doctors on CNN as well. Two of the four members on Gupta’s CNNHealth.com medical advisory team are Emory doctors.

You can see correspondent Gupta on “Paging Dr. Gupta” on CNN 6-10 a.m., Monday-Friday or read the Paging Dr. Gupta Blog.

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Translating research into life-saving

You or a loved one is suffering severe brain trauma in the wake of an accident. Imagine if doctors told you there was a treatment available that could up your chances of survival and even your chances at recovery. This isn’t just theoretical, because that’s an option some Emory patients have had, thanks to the availability of PROTECT, a progesterone-based treatment developed at Emory University and being administered by Emory trauma doctors.

Dr. Donald Stein, whose research led to the development of PROTECT, has just been honored by the Association for Psychological Science for his research and commitment to finding treatments and cures for traumatic brain injured patients.

Watch the video below to learn the real-life story of an accident victim who benefited from Stein’s work and the work of Emory’s doctors.

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Emory and the CDC

Centers for Disease Control and Prevention Headquarters

Centers for Disease Control and Prevention Headquarters

Today, as Dr. Thomas Frieden takes the helm of the Centers for Disease Control and Prevention (CDC), Emory’s own Dr. Kenneth Thorpe is providing expert commentary on President Barack Obama’s decision to name the former New York City health commissioner to the position and discussing what type of impact Frieden could make in the cheap oakley future.

The CDC, located adjacent to the Emory University campus, has strong ties to the university, including former CDC director, Dr. Jeffrey Koplan, who now heads Emory’s Global Health Institute. Many within the Emory’s Rollins School of Public Health have strong connections to the CDC.

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Emory docs make “House Calls”

If you watch the 8 a.m. hour of Fox 5 Atlanta’s “Good Day Atlanta,” you can see Grady Hospital-based internal medicine physicians Neil Winawer and Kimberly Manning. The doctors dispense medical information on Mondays and Wednesdays each week from the set of Fox 5’s “Good Day Housecall.” Following a crash course in broadcast journalism, the doctors research and write their own segments. Recent topics include swine flu, emergency contraception, brain trauma, and fitness in your 40s.

Manning joined the Emory faculty in 2001 and is program  director for maglie calcio poco prezzo Transitional Year Residency Program. Winawer, who is Manning’s faculty mentor, has been at Emory for 13 years Both doctors work at Grady Memorial Hospital in Downtown Atlanta. Read more about “Housecalls” on the Emory-Grady web site.

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Reaching out to Latinos

Diabetes is running rampant among the U.S. and one of the groups most affected is Latinos. Factors such as lack of English skills and cultural rules keep many Cheap Oakleys Latinos from  recognizing diabetes as a problem and seeking treatment.

Dr. Guillermo E. Umpierrez of Emory University is working to change that. Not only does he work daily at the Diabetes and Endocrinology Department at Atlanta’s Grady Memorial Hospital, but he recently spearheaded production an educational video aimed at the Latino population. Titled “Viva mas y major… con su diabetes bajo control” (“Live longer and better… with your diabetes under control,” the video is aimed at empowering patients to live their healthiest by controlling their diabetes. The vidoe was video produced by the Emory Latino Diabetes Education Program (ELDEP).

The 30-minute video is available online in five parts. Part one is below. The other segments are viewable on the Woodruff Health Sciences web site and on YouTube.

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