Monthly Archives: December 2011

mTOR inhibitors gaining favor for breast cancer treatment

December 9th, 2011 (No Comments)

This week, breast cancer researchers have been reporting encouraging clinical trial results with the drug everolimus at the San Antonio Breast Cancer Symposium. Everolimus is a mTOR inhibitor, first approved by the FDA for treatment of kidney cancer and then for post-transplant control of the immune system. Ruth O’Regan, MD, director of the Translational Breast […]

DNA copying problems explain muscular dystrophy mutations

December 1st, 2011 (No Comments)

Geneticist Madhuri Hegde and her colleagues have a paper in the journal Genome Researchthat addresses the question: where do copy number variations come from? Copy number variations (CNVs), which are deletions or duplications of small parts of the genome, have been the subject of genetic research for a long time. But only in the last […]